Bladder pain (Interstitial Cystitis) is caused by a chronic inflammation of the urinary bladder. This inflammation is associated with a relative thermal hyperalgesia referred to the hind limb. Palmitoylethanolamide (Normast) attenuates this referred hyperalgesia in a dose-depended fashion. These result implicates that Palmitoylethanolamide (Normast) can be seen as a novel treatment for bladder pain.
Normast Literature
Farquhar-Smith WP, Rice AS. Administration of endocannabinoids prevents a referred hyperalgesia associated with inflammation of the urinary bladder. Anesthesiology 2001; 94(3): 507-13
- Breakthrough in chronic pain treatment (Normast®)
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